MICROBIOME SKINCARE

The Biome Crowd™

Your skin is the largest organ, this much we know. But if you zoom in - really zoom in - what you may not know is that your skin is home to trillions of microorganisms, including beneficial bacteria, fungi, and viruses, all working together to create what we call the microbiome.01 

Who's on the door

A healthy skin barrier keeps the good stuff in (moisture, vitamins, protective lipids) and the bad stuff out (irritants, pollution, dirt). However, when our barrier is disrupted, our skin becomes dramatic — overreacting to everything from a weather change to a new face cream. This can make your skincare routine feel like you’re walking a tightrope.

BARRIER INTACT IRRITANTS STAY OUT WATER STAYS IN Cells packed, lipids between them
BARRIER DISRUPTED IRRITANTS GET IN WATER ESCAPES TWO GAPS, AND EVERYTHING MOVES Lipids missing, cells out of line
  • MICROBIOME
  • LIPIDS

Who's in the crowd

  • PREBIOTICFood for the bacteria02
  • PROBIOTICThe bacteria themselves03
  • POSTBIOTICWhat the bacteria make05

At SKINPOSSIBLE™, we ferment live strains of probiotics with aloe vera, licorice root, papaya, and pineapple.

How the crowd comes together

Bio-fermentation is a scientific process that involves using innovative ingredients extracted from natural raw materials to ferment strains of microorganisms (like probiotics). Through fermentation, active ingredients undergo a breakdown into smaller molecules, enhancing their absorption. This is also how we access the benefits of prebiotics and postbiotics.04

  • 01 · WE START WITH PLANTS
    02 · WE ADD THE MICROBES
    03 · THEY FERMENT TOGETHER
    04 · MOLECULES GET SMALLER

We make our formulas with live probiotics, which become shelf stable once the fermentation process is complete. The skin benefits are realised during the fermentation process.

We use the fermented cultures to formulate the products, not a filtered extract. Under the scientific consensus definition, a filtrate without cell components is not a postbiotic at all. 05

Every ingredient must earn its place

What we put into our formulations is equally as important as what we keep out. We combine bio-fermentation with high quality plant based ingredients to produce the prebiotics, probiotics and postbiotics, and leave out Possibly Problematic™ ingredients — so you can have your best, glowing complexion.

WHAT THE RESEARCH SAYS ABOUT MICROBIOME SKINCARE

  • 01BYRD, A. L., BELKAID, Y. & SEGRE, J. A. (2018). THE HUMAN SKIN MICROBIOME. NATURE REVIEWS MICROBIOLOGY 16, 143–155. doi.org/10.1038/nrmicro.2017.157
  • 02GIBSON, G. R. ET AL. (2017). ISAPP CONSENSUS STATEMENT ON THE DEFINITION AND SCOPE OF PREBIOTICS. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 14, 491–502. doi.org/10.1038/nrgastro.2017.75
  • 03HILL, C. ET AL. (2014). ISAPP CONSENSUS STATEMENT ON THE SCOPE AND APPROPRIATE USE OF THE TERM PROBIOTIC. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 11, 506–514. doi.org/10.1038/nrgastro.2014.66
  • 04PÉREZ-RIVERO, C. & LÓPEZ-GÓMEZ, J. P. (2023). UNLOCKING THE POTENTIAL OF FERMENTATION IN COSMETICS: A REVIEW. FERMENTATION 9(5), 463. doi.org/10.3390/fermentation9050463
  • 05SALMINEN, S. ET AL. (2021). ISAPP CONSENSUS STATEMENT ON THE DEFINITION AND SCOPE OF POSTBIOTICS. NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY 18, 649–667. doi.org/10.1038/s41575-021-00440-6
  • 06ZIEMLEWSKA, A. ET AL. (2025). ENHANCING THE COSMETIC POTENTIAL OF ALOE VERA GEL BY KOMBUCHA-MEDIATED FERMENTATION: PHYTOCHEMICAL ANALYSIS AND EVALUATION OF ANTIOXIDANT, ANTI-AGING AND MOISTURIZING PROPERTIES. MOLECULES 30(15), 3192. doi.org/10.3390/molecules30153192
  • 07FEI, W., NODA, M., DANSHIITSOODOL, N. & SUGIYAMA, M. (2024). SKIN ANTI-AGING EFFICACY OF A LACTOBACILLUS PLANTARUM GT-17F FERMENTED DENDROBIUM OFFICINALE INGREDIENT: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL STUDY. COSMETICS 11(1), 26. doi.org/10.3390/cosmetics11010026
  • 08ALBOUY, M. ET AL. (2023). SKIN-PROTECTIVE BIOLOGICAL ACTIVITIES OF BIO-FERMENTED AFRAMOMUM ANGUSTIFOLIUM EXTRACT BY A CONSORTIUM OF MICROORGANISMS. FRONTIERS IN PHARMACOLOGY 14, 1303198. doi.org/10.3389/fphar.2023.1303198

THESE ARE EXTERNAL REFERENCES AND NOT STUDIES CONDUCTED BY SKINPOSSIBLE™.

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